Panera Bread 1684 Massachusetts Ave, Lexington, MA02420 This Panera Bread is a full bakery-cafe location of the national chain. Panera specializes in its fresh, oven-baked…More bread, and offers bakery and cafe menus. The cafe menu features hand-tossed salads, specialty sandwiches and paninis, pasta, stew, and soups, and smoothies, coffee and tea. The bakery offers pastries and sweets, breakfast items and fresh baked breads. Panera has a cozy and comfortable environment.